Research Associate / Scientist (Ref 4255)

| Permanent

Artios Pharma is currently recruiting for a cell and molecular biologist. This is an excellent opportunity to join a world class research team in a new dynamic Biotech company based south of Cambridge, UK. Artios is focused on identifying and developing cancer treatments by exploiting novel targets within the DNA damage response (DDR), a scientific area of high expectation following the success of PARP inhibitors in the clinic. The company is actively building an exciting portfolio of unique DDR projects and has the ambitious aim to quickly translate these discoveries into the clinic.

We currently have two programmes in early phases of clinical development. These phase 1/2a studies are evaluating the small-molecule ATR inhibitor ART0380 and the first-in-class Pol Theta inhibitor ART4215 in patients with advanced or metastatic solid tumours.

Outline of the Role

You will join the Genetic Screening team to identify biomarkers of sensitivity for the Artios’ proprietary compounds. Your primary responsibility will be developing and performing CRISPR screens with Artios’ proprietary compounds as well as hit validation using gene editing and diverse cell viability assays. You will apply your technical expertise in cellular and molecular biology, contribute biological data to Artios’ ongoing drug discovery projects and you will have the opportunity to work in multi-disciplinary collaborative networks, involving CRO’s and academic scientists.

Appointment will be at the Research Associate/Scientist level depending on experience.

Qualifications and Experience

  • BSc, MSc and/or Ph.D. or equivalent experience in the private research sector

Key Skills and Abilities

  • Experience in basic molecular and cell biology techniques, specifically cell culture and proliferation/viability assays
  • Experience in CRISPR screening and gene
  • Editing via CRISPR/Cas9
  • Experience in FACS, western blot, imaging is desirable
  • Enthusiasm and commitment to achieve within tight deadlines
  • Knowledge of DDR and cancer drug discovery is desirable
  • Ability to work independently in an organised and methodical fashion
  • Good level of IT literacy
  • Excellent communication, team working and presentation skills

 

This is a permanent position, offering an attractive salary & benefits package. If you have the right background, then please apply by sending your CV with a covering letter quoting Ref 4255 using the link below.

https://hr.breathehr.com/v/research-associate-scientist-4255-24258

The closing date is Wednesday 31st August 2022.

In order to comply with UK Employment Law, all applicants must have the Right to Work in the UK or if from the EU/outside the EU, subject to receiving a relevant Skilled Worker Visa to work in the UK.

Due to the high volume of applications we receive; if you do not hear from us we will not be inviting you to interview on this occasion.

No agencies, thank you.