Scientist (Ref: 4307)

Artios Pharma is currently recruiting a Scientist to join our world class research team in a dynamic, expanding biotech company based south of Cambridge, UK. Artios is focused on identifying and developing cancer treatments by exploiting novel targets within the DNA damage response (DDR), a scientific area of high expectation following the success of PARP inhibitors in the clinic.

Outline of the role

Primary responsibility will be contributing biological data to Artios’ early-stage drug discovery projects.  Using genetic, cell biological and pharmacological strategies to identify and validate therapeutic targets, delivering high quality cell biological and mode of action data packages.  Working in multi-disciplinary collaborations involving a high level of teamwork.

Responsibilities:

• Apply expertise in cell and molecular biology to run mechanistic cell biological studies to identify, validate and characterise Artios’ novel targets.
• Contribute biological data to Artios’ ongoing drug discovery projects.

Skills, Experience & Qualifications:

Essential

• Excellent skills in a broad range of cell and molecular biology techniques, including mammalian cell culture, viability assays, Western blotting, immunofluorescence.
• Demonstratable experience of working in a research environment.
• High level of team working skills.
• Ability to work independently as well as part of a team in an organised and methodical fashion.
• Ability to troubleshoot experiments independently.
• Excellent communication and presentation skills.
• Excellent attention to detail.
• Keeping accurate laboratory records.
• High level of IT literacy.
• Flexible approach to change.
• PhD or equivalent in a life science subject.

Desirable

• Understanding of DNA damage response biology, DNA repair pathways and/or cancer biology.
• Expertise in cell-based screening assays.
• Experience with stable cell line generation.
• Experience of small molecule drug discovery.
• Experience working in an industrial setting.